Jones Chest 2011 – Lactate vs ScvO2

Short Citation: Chest 2011;140(6):1406-8.

PubMed PMID: 22147817

Full Citation: Jones AE. Point: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? Yes. Chest 2011;140(6):1406-8.

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Authors' Conclusions: Early sepsis resuscitation remains a dynamic topic of research interest, with many important questions that have yet to be answered. As summarized in this report, the best available evidence suggests that if a clinician has to choose a single goal of early sepsis resuscitation, lactate clearance, as opposed to Scvo2, is the more appropriate goal to choose.

Additional comments from Journal Gems contributors: For another viewpoint, read this counterpoint Editorial by Dr Emanuel Rivers.

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