Short Citation: Chest 2011;140(6):1406-8.
PubMed PMID: 22147817
Full Citation: Jones AE. Point: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? Yes. Chest 2011;140(6):1406-8.
Organ System: Cardiovascular
Science Area: Measurement / Investigation / Monitoring / Equipment
Article Type: Editorial
Authors' Conclusions: Early sepsis resuscitation remains a dynamic topic of research interest, with many important questions that have yet to be answered. As summarized in this report, the best available evidence suggests that if a clinician has to choose a single goal of early sepsis resuscitation, lactate clearance, as opposed to Scvo2, is the more appropriate goal to choose.
Additional comments from Journal Gems contributors: For another viewpoint, read this counterpoint Editorial by Dr Emanuel Rivers.