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REASON

Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study.

Non-cardiac surgical patients, age 70+, 5% 30-day mortality, 20% 30-day complications, 9.4% ICU admission. Preop risk factors for mortality: age 80+, ASA 3+, albumin < 30, emergency surgery. Complications associated with mortality: AKI, unplanned ICU admission, systemic inflammation. Patient factors had stronger association than type of surgery.

GeneralLandmarkCohort·Anaesthesia·2010·4,158 patients

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HES vs NS. No difference in 90-day mortality. HES group had more RRT (7% vs 5.8%)

N Engl J Med·2012

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