-

Counterpoint: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? No.

Chest 2011

http://www.ncbi.nlm.nih.gov/pubmed/22147818

https://doi.org/10.1378/chest.11-2563

Notes

Lactate should NOT be used instead of ScvO2 (CVC) for GDT in severe sepsis / septic shock

Abstract